How to increase your click through rate (CTR) with google adsense

1. Move your ads as close to your main content as much as your a comfortable with. Ads that are placed closer to the main content of the page tend to have a higher click through rate (on average).
2. Experiment with the color scheme and layout of the adsense ads. Ad formats which more closely match the overall look and feel of your website tend to do better on average. This may seem counterintuitive at first, as you might think that ads which stand out more are more likely to be clicked on. You can customize the text color, link color, background color, and border color of displayed adsense ads.

3. Focus your content on each page as much as possible. In other words, the more coherent the content on the page, the more likely that the ads which are displayed will be relevant to a visitor. The more relevant the ad, the more likely the user may click on the ad link to find other information.
4. If you are using Adsense on a blog, there are a number of extensions which can help increase earnings. For example, there are many free Wordpress plugins which further help manage your Google Adsense ads on your blog. You can customize your blog by showing more ads to the visitor when the visitor arrives via a search engine and/or visits a post that is older than a certain number of days. Visitors who visit a page from a search engine may be more likely than other types of users to click on an ad as they surf around. So consider using a plugin which offers even more possibilities for customization beyond simply changing the look and feel of the ads themselves.
5. Experiment by switching between text ads and image ads. You may find that you get a higher CTR on one or the other. This also helps you further find the right mix of text and graphics on your site, which may vary based on your content.